Photo of Lanchun Lu, Ph D, DABR.

Lanchun Lu, Ph D, DABR.

  • Assistant Professor, Radiation Oncology
    The Ohio State University
  • lu.281@osu.edu
  • Department of Radiation Oncology and The James Cancer Hospital & Solove Research Institute
    Columbus, Ohio 43210
  • Phone: 6143669307

Research Interests

Optical Coherence Tomography for cancer diagnosis and treatment, Image-guide radiation therapy, radio-resistance of cancers.

Professional Interests

Image-guided radiation therapy, Gamma Knife Radiosurgery, Linac-based SBRT and SRS.
  • Most Common Publication Keywords # of Pubs
  • AAPM TG-61 REPORT1
  • BEAM DOSIMETRY1
  • CALIBRATION1
  • CELL/SMALL ANIMAL EXPERIMENTS1
  • DOSE GRADIENT1
  • NANODOT DOSIMETER1
  • PROTOCOL1
  • RS 2000 X-RAY BIOLOGICAL IRRADIATOR1
  • Most Common Publication Subject Categories # of Pubs
  • BIOLOGY1
  • CLINICAL NEUROLOGY1
  • NUCLEAR SCIENCE & TECHNOLOGY1
  • ONCOLOGY1
  • RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING1

Most Recent Journal Articles

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  • Eric Allan, Lanchun Lu, Hooman Hamedani,Virginia Diavolitsis, Aashish Bhatt, John Grecula, Jessica Wobb, Tiffany Kessling, Meade Van Putten, Dukagjin Blakaj. "Dosimetric Verification of Dental Stent Efficacy in Head and Neck Radiation Therapy Using Modern Radiation Therapy Techniques: Quality of Life and Treatment Compliance Implications." Journal of Radiation Oncology. Vol. http://link.springer.com/article/10.1007/s13566-016-0268-1?wt_mc=Internal.Event.1.SEM.ArticleAuthorO, no. First online: 08 August 2016. (Aug 2016): pp 1-8 http://link.springer.com/article/10.1007/s13566-016-0268-1?wt_mc=Internal.Event.1.SEM.Article. (Published). Eric Allan, Lanchun Lu, Hooman Hamedani,Virginia Diavolitsis, Aashish Bhatt, John Grecula, Jessica Wobb, Tiffany Kessling, Meade Van Putten, Dukagjin Blakaj Dosimetric Verification of Dental Stent Efficacy in Head and Neck Radiation Therapy Using Modern Radiation Therapy Techniques: Quality of Life and Treatment Compliance Implications Journal of Radiation Oncology Journal Article Peer-Review
  • Shuting Zhao, Lingling Zhang, Jianfeng Han, Jianhong Chu, Hai Wang, Xilin Chen, Youwei Wang, Lanchun Lu, Xuefeng Bai,Yearsley Martha, Steven Devine, Xiaoming He, Jianhua Yu. "Conformal Nanoencapsulation of Allogeneic T Cells Mitigates Graft-Versus-Host Disease and Retains Graft-Versus-Leukemia Activity." ACS Nano. Vol. DOI: 10.1021/acsnano.6b02206, (May 2016): ACS Nano. 2016 May 25. [Epub ahead of print]. (Published). Shuting Zhao, Lingling Zhang, Jianfeng Han, Jianhong Chu, Hai Wang, Xilin Chen, Youwei Wang, Lanchun Lu, Xuefeng Bai,Yearsley Martha, Steven Devine, Xiaoming He, Jianhua Yu Conformal Nanoencapsulation of Allogeneic T Cells Mitigates Graft-Versus-Host Disease and Retains Graft-Versus-Leukemia Activity ACS Nano Journal Article Peer-Review 10.1021/acsnano.6b02206 DOI
  • Cancan Zhang, Nina A. Mayr, Simon S. Lo, Lanchun Lu, Kaile Li, Yi Zheng, William T.C. Yuh, Zhibin Huang. "The α/β Ratio Dose‐range Independent: Application of the Generalized Linear‐quadratic (gLQ) Model." Journal of Radiation Oncology. Vol. 4, no. 3. (Sep 2015): pp 309-314. (Published). Cancan Zhang, Nina A. Mayr, Simon S. Lo, Lanchun Lu, Kaile Li, Yi Zheng, William T.C. Yuh, Zhibin Huang The α/β Ratio Dose‐range Independent: Application of the Generalized Linear‐quadratic (gLQ) Model Journal of Radiation Oncology Journal Article Peer-Review
  • Lanchun Lu*, Jonathan Filippi, Akshi Patel, Nilendu Gupta, Michael Weldon, Jeffery Woollard, Ahmet Ayan, Yi Rong, Douglas Martin, Christopher Pelloski, Meng Xu Welliver. "A Clinical Dosimetry Analysis of Total Body Irradiation for Leukemia Patients." International Journal of Medical Physics, Clinical Engineering and Radiation Oncology. Vol. 3, no. 1. (Feb 2014): 31-42. (Published). Lanchun Lu*, Jonathan Filippi, Akshi Patel, Nilendu Gupta, Michael Weldon, Jeffery Woollard, Ahmet Ayan, Yi Rong, Douglas Martin, Christopher Pelloski, Meng Xu Welliver A Clinical Dosimetry Analysis of Total Body Irradiation for Leukemia Patients International Journal of Medical Physics, Clinical Engineering and Radiation Oncology Journal Article Peer-Review
  • Lu,Lanchun*; Bondra,Kathryn; Gupta,Nilendu; et al. "Using NanoDot dosimetry to study the RS 2000 X-ray Biological Irradiator." INTERNATIONAL JOURNAL OF RADIATION BIOLOGY. Vol. 89, no. 12. (Dec 2013): 1094-1099. (Published).Citation Count: 1. Lu,Lanchun*; Bondra,Kathryn; Gupta,Nilendu; Sommerfeld,James; Chronowski,Christopher; Leasure,Justin; Singh,Mamata; Pelloski,Christopher,E Using NanoDot dosimetry to study the RS 2000 X-ray Biological Irradiator INTERNATIONAL JOURNAL OF RADIATION BIOLOGY Journal Article Peer-Review 23786571 10.3109/09553002.2013.817703 0955-3002 Purpose: To use NanoDot dosimeters to study the RS 2000 X-ray Biological Irradiator dosimetry characteristics and perform in vivo dosimetry for cell or small animal experiments. Methods and materials: We first calibrated the Landauer NanoDot (TM) Reader by irradiating some NanoDot dosimeters with a set of known doses at specific positions defined by the irradiator. A group of five NanoDot dosimeters were placed at five specific positions where the dose rates were known and provided by the irradiator. Each group was irradiated for a set of times respectively. By correlating the readings of dosimeters with the given irradiated doses, we established the dose-reading relationship for the irradiator under the specific running condition. The established calibration curve was validated by exposing arbitrary known doses to a set of dosimeters, using the Landauer NanoDot (TM) Reader to measure the doses, and then making the comparison between the two doses. To study the dose gradient of the X-ray inside the irradiated target (dose variation/cm), we placed dosimeters under different thicknesses of water-equivalent bolus and irradiated them, then measured the doses to determine the dose gradient. Results: Using the method described above, we were able to calibrate the Landauer InLight NanoDot (TM) Reader and use NanoDot dosimeters to measure the actual doses delivered to the targets for the cell/small animal experiments that use the RS 2000 X-ray Biological Irradiator. Conclusions: NanoDots are ideal dosimeters to use for in vivo dosimetry for cell/small animal irradiation experiments. The dose decrease inside the animal tissue is about 20% per cm. PROTOCOL|BEAM DOSIMETRY|AAPM TG-61 REPORT|calibration|dose gradient|cell/small animal experiments|NanoDot dosimeter|RS 2000 X-ray Biological Irradiator Biology|Nuclear Science & Technology|Radiology, Nuclear Medicine & Medical Imaging Links

Most Recent Scholarly Presentations

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  • Lanchun Lu*, Presenter. "Endoscopic 3-D OCT-Guided Brachytherapy for Early Stage Pancreatic Cancers." Presented at ASTRO 2016, Boston, United States. (Sep 2016) Lanchun Lu* Endoscopic 3-D OCT-Guided Brachytherapy for Early Stage Pancreatic Cancers Presenter 1 ASTRO 2016 Scientific Session Title: Physics - Innovative Technologies National Principle Investigator
  • Malorie Stowe, Presenter. "Quantification of 3D Geometric Distortion for 1.5T and 3T MRI Scanners Used for Radiation Therapy." Presented at AAPM 2016, Washington D.C., United States. (Jul 2016) Malorie Stowe Quantification of 3D Geometric Distortion for 1.5T and 3T MRI Scanners Used for Radiation Therapy Presenter 1 AAPM 2016 National Principle Investigator and advisor.
  • Christian Barney, Presenter. "The effect of tissue heterogeneity on Gamma Knife dosimetry in the treatment of pituitary and parasellar tumors." Presented at The Leksell Gamma Knife® Society 2016, Amsterdam, The Netherlands, Netherlands. (May 2016) Christian Barney The effect of tissue heterogeneity on Gamma Knife dosimetry in the treatment of pituitary and parasellar tumors Presenter 1 The Leksell Gamma Knife® Society 2016 International Principal Investigator and advisor.
  • Lanchun Lu, Presenter. "Activation-Induced Cytidine Deaminase Confers Cancer Resistance to Radiation Therapy." Presented at AAPM 2015, Peers within Field., Anaheim, California, United States. (Jul 2015) Lanchun Lu Activation-Induced Cytidine Deaminase Confers Cancer Resistance to Radiation Therapy Presenter 1 AAPM 2015 National
  • Lanchun Lu, Presenter. "Dosimetric Study of Radiation Therapy for Head/Neck Patients with Metallic Dental Fixtures." Presented at AAPM 2015, Peers within Field., Anaheim, California, United States. (Jul 2015) Lanchun Lu Dosimetric Study of Radiation Therapy for Head/Neck Patients with Metallic Dental Fixtures Presenter 1 AAPM 2015 National